Immunology
We investigate immune regulation and disease mechanisms using quantitative and single-cell approaches.
Engineering precision immune therapies & diagnostics
Lab Overview
The Mahajan Lab is based in the Division of Engineering in Medicine and the Center for Engineered Therapeutics at BWH. We develop engineered therapeutics and diagnostics for immune-mediated diseases by integrating nanoparticle platforms, medicinal chemistry, computational modeling, and high-dimensional experimental approaches. Our research spans multiple scales from rational molecular design to in vivo model systems with a focus on immune regulation, autoimmune diseases, and the development of precision nanomedicines and ultra-sensitive diagnostics.
Research
Therapeutics
We engineer targeted biologics, nanoparticles, and conjugates for modulating immune responses.
Diagnostics
We develop ultra-sensitive diagnostics to enable early detection, precise monitoring, and better clinical outcomes.